Different effects of bladder distention on point a-based and 3D-conformal intracavitary brachytherapy planning for cervical cancer
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Authors
Ju, Sang Gyu
Huh, Seung Jae
Shin, Jung Suk
Park, Won
Nam, Heerim
Bae, Sunhyun
Oh, Dongryul
Hong, Chae-Seon
Kim, Jin Sung
Han, Youngyih
Issue Date
2012-10-26
Type
Article
Language
en_US
Keywords
Intracavitary Brachytherapy , Bladder Distention , 3D-Conformal Intracavitary Brachytherapy , Cervical Cancer
Alternative Title
Abstract
This study sought to evaluate the differential effects of bladder distention on point A-based (AICBT) and three-dimensional conformal intracavitary brachytherapy (3D-ICBT) planning for cervical cancer. Two sets of CT scans were obtained for ten patients to evaluate the effect of bladder distention. After the first CT scan, with an empty bladder, a second set of CT scans was obtained with the bladder filled. The clinical target volume (CTV), bladder, rectum, and small bowel were delineated on each image set. The AICBT and 3D-ICBT plans were generated, and we compared the different planning techniques with respect to the dose characteristics of CTV and organs at risk. As a result of bladder distention, the mean dose (D50) was decreased significantly and geometrical variations were observed in the bladder and small bowel, with acceptable minor changes in the CTV and rectum. The average D2 cm3and D1 cm3showed a significant change in the bladder and small bowel with AICBT; however, no change was detected with the 3D-ICBT planning. No significant dose change in the CTV or rectum was observed with either the AICBT or the 3D-ICBT plan. The effect of bladder distention on dosimetrical change in 3D-ICBT planning appears to be minimal, in comparison with AICBT planning.
Description
Citation
Ju, S. G., Huh, S. J., Shin, J. S., Park, W., Nam, H., Bae, S., Oh, D., Hong, C. S., Kim, J. S., Han, Y., & Choi, D. H. (2013). Different effects of bladder distention on point A-based and 3D-conformal intracavitary brachytherapy planning for cervical cancer. Journal of radiation research, 54(2), 349–356. https://doi.org/10.1093/jrr/rrs091
Publisher
Journal of Radiation Research