Conservative treatment in early cervical cancer
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Authors
Karimi-Zarchi, Mojgan
Mousavi, Azamsadat
Gilani, Mitra Modares
Barooti, Esmat
Miratashi-Yazdi, Ashrafosadat
Dehghani, Atefe
Issue Date
2013-09
Type
Article
Language
en_US
Keywords
Cervical Cancer , Early Stage Cervical Cancer , Conservative , Quality of Life , Fertility Preservation
Alternative Title
Abstract
Purpose of review: The aim of this study was to describe fertility preservation methods to improve quality of life of early stages of cervical cancer. Recent finding: Although definite treatment of early stages of cervical cancer including stages IA,IB1 and IIA non-bulky is radial hysterectomy, this method is used in perimenopousal period in which fertility preservation is not important. Whenever fertility preservation is so important, some methods like radical trachelectomy and laparoscopic lymphadenectomy are used to rule out lymphatic metastases. Summary: If any visible lesion on cervix is found, pelvic MRI is helpful and during operation, trachelectomy samples are sent for frozen section and margin study. Radical trachelectomy is done vaginal or abdominal. Overall relapse rate of cervical cancer in radical trachelectomy and radical hysterectomy is the same. Complications of radical trachelectomy include chronic vaginal discharge, abnormal uterine bleeding, dysmenorrhea, inflammation and ulcer due to cercelage, amenorrhea, cervical stenosis and pregnancy complications following trachelectomy including 2nd trimester abortion and premature labor following cervical prematurity.The best and preferred method of labor is cesarean section. Neoadjuant chemotherapy followed by radical trachelectomy in large cervical lesions is a suitable treatment. Ultraconservative operations like large cold knife conization, simple trachelectomy with laparoscopic lymphadenectomy and sentinel lymph node mapping are suitable for very small lesions.
Description
Citation
Karimi-Zarchi, M., Mousavi, A., Gilani, M. M., Barooti, E., Miratashi-Yazdi, A., & Dehghani, A. (2013). Conservative treatment in early cervical cancer. International journal of biomedical science : IJBS, 9(3), 123–128.
Publisher
International Journal of Biomedical Science : IJBS