Successful treatment of locally advanced bulky cervical cancer complicated by irreducible complete uterine prolapse

Lee, Dong Hyung; Joo, Jong Kil; Suh, Dong Soo; Shin, Byung Sup; Hwang, Seo Yoon; Kim, Ki Hyung

Successful treatment of locally advanced bulky cervical cancer complicated by irreducible complete uterine prolapse

Files

medi-101-e28664.pdf (757.82 KB)

Authors

Lee, Dong Hyung

Joo, Jong Kil

Suh, Dong Soo

Shin, Byung Sup

Hwang, Seo Yoon

Kim, Ki Hyung

Issue Date

2022-01-21

Type

Article

Language

en_US

Keywords

Advanced Bulky Carcinoma , Cervical Cancer , Uterine Prolapse

Abstract

Rationale: Cervical cancer complicated by irreducible complete uterine prolapse in elderly patients is extremely rare. No standard treatment has been established for these conditions. Patient concerns: A 74-year-old woman with a 30-year history of pelvic organ prolapse presented with irreducible complete uterine prolapse and a large exophytic mass involving the cervix and vaginal wall. Diagnosis: Biopsy of the mass was performed at the referring institution and showed invasive verrucous-type squamous cell carcinoma. Interventions: A prolapsed uterus with a tumor mass could not be manually reduced. After completion of concurrent chemoradiotherapy, the tumor mass in the prolapsed uterus decreased and could be reduced manually. Subsequently, the patient underwent hysterectomy and intra-abdominal uterosacral ligament suspension. Outcomes: At 19 months of postoperative follow-up, the patient remained disease-free and had no evidence of vault prolapse. Lessons: This study has important clinical implications and may provide a therapeutic strategy to address unmet medical needs in combination with locally advanced cervical cancer complicated by irreducible complete uterine prolapse. These conditions were successfully treated using a multidisciplinary approach of chemoradiotherapy followed by radical hysterectomy and uterosacral ligament suspension.

Citation

Lee, D. H., Joo, J. K., Suh, D. S., Shin, B. S., Hwang, S. Y., & Kim, K. H. (2022). Successful treatment of locally advanced bulky cervical cancer complicated by irreducible complete uterine prolapse: A case report. Medicine, 101(3), e28664. https://doi.org/10.1097/MD.0000000000028664

Publisher

Medicine