Pelvic exenteration for recurrent cervical cancer: ten-year experience at National Cancer Center in Korea
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Authors
Yoo, Heon Jong
Lim, Myong Cheol
Seo, Sang-Soo
Kang, Sokbom
Yoo, Chong Woo
Kim, Joo-Young
Park, Sang-Yoon
Issue Date
2012-09-19
Type
Article
Language
en_US
Keywords
Gynecological Malignancies , Pelvic Exenteration , Surgical Outcomes
Alternative Title
Abstract
Objective:
To evaluate survival and morbidity after pelvic exenteration (PE) for the curative management of recurrent cervical cancer.
Methods:
We retrospectively evaluated patients with recurrent cervical cancer who underwent PE from January 2001 to April 2011. Patients were identified from the registry of our institution. The clinical status and demographic information was obtained by reviewing the medical records.
Results:
Sixty-one recurrent cervical cancer patients underwent PE. Patients who received radiotherapy, operation, chemotherapy before PE were 98%, 41%, and 23%, respectively. The total morbidity rate was 44%; 10 (16%) patients had early complications (30 days or less after PE), whereas 22 (36%) patients had late complications. Wound problems were common early complications (7/18), and bowel fistulas were common late complications (9/30). The five-year overall survival and five-year disease-free survival were 56% and 49%, respectively. Median follow-up was 22 months (range, 1.8 to 60 months). Affecting factors for overall survival were resection margin status, pelvic wall and rectal involvement.
Conclusion:
Our overall 5-year survival is encouraging. Although the morbidity rate is still high, PE is a potentially curative opportunity in gynecological malignancies with no other treatment options. The most important factors for overall survival after PE are the resection margin status, pelvic wall involvement and rectal involvement.
Description
Citation
Yoo, H. J., Lim, M. C., Seo, S. S., Kang, S., Yoo, C. W., Kim, J. Y., & Park, S. Y. (2012). Pelvic exenteration for recurrent cervical cancer: ten-year experience at National Cancer Center in Korea. Journal of gynecologic oncology, 23(4), 242–250. https://doi.org/10.3802/jgo.2012.23.4.242
Publisher
Journal of Gynecologic Oncology