Prevalence and risk factors associated with precancerous cervical cancer lesions among HIV-infected women in resource-limited settings
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Authors
Memiah, Peter
Mbuthia, Wangeci
Kiiru, Grace
Agbor, Solomon
Odhiambo, Francesca
Ojoo, Sylvia
Biadgilign, Sibhatu
Issue Date
2012-04-04
Type
Article
Language
en_US
Keywords
Prevalence , Risk Factors , Precancerous Cervical Cancer Lesions , HIV-Infected Women
Alternative Title
Abstract
Objective. To assess the prevalence and identified associated risk factors for precancerous cervical cancer lesions among HIV-infected women in resource-limited settings in Kenya. Methods. HIV-infected women attending the ART clinic at the Nazareth Hospital ART clinic between June 2009 and September 2010. Multivariate logistic regression model with odds ratios and 95% confidence intervals (CI) were estimated after controlling for important covariates. Result. A total of 715 women were screened for cervical cancer. The median age of the participants was 40 years (range 18–69 years). The prevalence of precancerous lesions (CINI, CINII, CIN III, ICC) was 191 (26.7%). After controlling for other variables in logistic regression analysis, cervical precancerous lesions were associated with not being on ART therapy; whereby non-ART were 2.21 times more likely to have precancerous lesions than ART patients [(aOR) = 2.21, 95% CI (1.28–3.83)]. Conclusion. The prevalence of precancerous cervical lesions was lower than other similar settings. It is recommended that cancer screening of HIV-infected women should be an established practice. Availability and accessibility of these services can be done through their integration into HIV. Prompt initiation of HAART through an early enrollment into care has an impact on reducing the prevalence and progression of cervical precancerous lesions.
Description
Citation
Memiah, P., Mbuthia, W., Kiiru, G., Agbor, S., Odhiambo, F., Ojoo, S., & Biadgilign, S. (2012). Prevalence and Risk Factors Associated with Precancerous Cervical Cancer Lesions among HIV-Infected Women in Resource-Limited Settings. AIDS research and treatment, 2012, 953743. https://doi.org/10.1155/2012/953743
Publisher
AIDS Research and Treatment