Economic evaluation of three populational screening strategies for cervical cancer in the county of Valles Occidental: CRICERVA clinical trial
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Authors
Acera, Amelia
Rodriguez, Ana
Trapero-Bertran, Marta
Soteras, Pilar
Sanchez, Norman
Bonet, Josep M.
Manresa, Josep M.
Hidalgo, Pablo
Toran, Pere
Prieto, Gemma
Issue Date
2011-10-19
Type
Article
Language
en_US
Keywords
Economic Evaluation , Cervical Cancer , Valles Occidental , CRICERVA Clinical Trial
Alternative Title
Abstract
Background:
A high percentage of cervical cancer cases have not undergone cytological tests within 10 years prior to diagnosis. Different population interventions could improve coverage in the public system, although costs will also increase. The aim of this study was to compare the effectiveness and the costs of three types of population interventions to increase the number of female participants in the screening programmes for cancer of the cervix carried out by Primary Care in four basic health care areas.
Methods/Design:
A cost-effectiveness analysis will be performed from the perspective of public health system including women from 30 to 70 years of age (n = 20,994) with incorrect screening criteria from four basic health care areas in the Valles Occidental, Barcelona, Spain. The patients will be randomly distributed into the control group and the three intervention groups (IG1: invitation letter to participate in the screening; IG2: invitation letter and informative leaflet; IG3: invitation letter, informative leaflet and a phone call reminder) and followed for three years. Clinical effectiveness will be measured by the number of HPV, epithelial lesions and cancer of cervix cases detected. The number of deaths avoided will be secondary measures of effectiveness. The temporal horizon of the analysis will be the life expectancy of the female population in the study. Costs and effectiveness will be discounted at 3%. In addition, univariate and multivariate sensitivity analysis will be carried out.
Discussion:
IG3 is expected to be more cost-effective intervention than IG1 and IG2, with greater detection of HPV infections, epithelial lesions and cancer than other strategies, albeit at a greater cost.
Description
Citation
Acera, A., Rodriguez, A., Trapero-Bertran, M., Soteras, P., Sanchez, N., Bonet, J. M., Manresa, J. M., Hidalgo, P., Toran, P., & Prieto, G. (2011). Economic evaluation of three populational screening strategies for cervical cancer in the county of Valles Occidental: CRICERVA clinical trial. BMC health services research, 11, 278. https://doi.org/10.1186/1472-6963-11-278
Publisher
BMC Health Services Research