Sexually transmitted infections and semen quality from subfertile men with and without leukocytospermia
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Authors
Bai, Shun
Li, Yuan
Wan, Yangyang
Guo, Tonghang
Jin, Qi
Liu, Ran
Tang, Wenjuan
Sang, Meiying
Tao, Yuanyuan
Xie, Baoguo
Issue Date
2021-06-21
Type
Article
Language
en_US
Keywords
Leukocytospermia , Sexually Transmitted Infections , Semen Parameters
Alternative Title
Abstract
Background: The role of sexually transmitted infections (STIs) in semen parameters and male infertility is still a controversial area. Previous studies have found bacterial infection in a minority of infertile leukocytospermic males. This study aims to investigate the prevalence of STIs in semen from subfertile men with leukocytospermia (LCS) and without leukocytospermia (non-LCS) and their associations with sperm quality.
Methods: Semen samples were collected from 195 men who asked for a fertility evaluation. Infection with the above 6 pathogens was assessed in each sample. Sperm quality was compared in subfertile men with and without LCS.
Results: The LCS group had significantly decreased semen volume, sperm concentration, progressive motility, total motility and normal morphology. The infection rates of Ureaplasma urealyticum (Uuu), Ureaplasma parvum (Uup), Mycoplasma hominis (MH), Mycoplasma genitalium (MG), Chlamydia trachomatis (CT), herpes simplex virus-2 (HSV-2) and Neisseria gonorrhoeae (NG) were 8.7 %, 21.0 %, 8.2 %, 2.1 %, 3.6 %, 1.0 and 0 %, respectively. The STI detection rates of patients with LCS were higher than those of the non-LCS group (52.3 % vs. 39.3 %), although there was no statistically significant difference between the two groups (P = 0.07). All semen parameters were not significantly different between LCS with STIs and without STIs, except the semen volume in the MG-infected patients with LCS was significantly lower than that in the noninfected group.
Conclusions: LCS was associated with a reduction in semen quality, but was not associated with STIs.
Description
Citation
Bai, S., Li, Y., Wan, Y., Guo, T., Jin, Q., Liu, R., Tang, W., Sang, M., Tao, Y., Xie, B., Zhao, Y., Li, W., Xu, X., Yue, Q., Hu, X., & Xu, B. (2021). Sexually transmitted infections and semen quality from subfertile men with and without leukocytospermia. Reproductive biology and endocrinology : RB&E, 19(1), 92. https://doi.org/10.1186/s12958-021-00769-2
Publisher
Reproductive Biology and Endocrinology : RB&E