Neuroendocrine differentiation in a case of cervical cancer
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Authors
Mohamed, Rashed Mona
Alemayehu, Bekele
Issue Date
2010-07-28
Type
Article
Language
en_US
Keywords
Cervical Cancer , Cervix , Chromogranine A , Small Cell Carcinoma
Alternative Title
Abstract
Neuroendocrine neoplasms may occur in the uterine cervix, although rarely; it accounts for 0.5-1% of all malignant tumors of the uterine cervix. A case report of an Ethiopian female presented at the Gynecology Out-Patient Clinic at Jimma University Hospital, complaining from irregular vaginal bleeding over the previous three months. Clinically there was a cauliflower cervical mass; histopathologically it was formed of sheets of small cell tumor; that further showed neuroendocrine differentiation, as demonstrated by chromogranin-A positivity. It is important to differentiate small cell carcinoma from other malignant tumors of the uterine cervix. Morphological features play an important role in making a diagnosis and the immunohistochemistry study can offer an additional useful assistance.
Description
Citation
Rashed, M. M., & Bekele, A. (2010). Neuroendocrine differentiation in a case of cervical cancer. The Pan African medical journal, 6, 4.
Publisher
The Pan African Medical Journal