The clinical role of HPV testing in primary and secondary cervical cancer screening
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Authors
Hoste, G.
Vossaert, K.
Poppe, W. A. J.
Issue Date
2013-07-01
Type
Article
Language
en_US
Keywords
Clinical Role of HPV Testing , Primary and Secondary Cervical Cancer Screening
Alternative Title
Abstract
Traditional population-based cervical screening programs, based on cytology, have successfully reduced the burden of cervical cancer. Nevertheless limitations remain and new screening methods are emerging. Despite vaccination against the 2 most oncogenic types (HPV 16/18), cervical cancer screening will have to continue as an essential public health strategy. As the acquisition of an HR-HPV infection is critical in the progression to (pre-)cancerous cervical lesions, recent research has focused on HR-HPV detection. The sensitivity of HPV testing in primary and secondary prevention outweighs that of cytology, at the cost of slightly lower specificity. Although most of the HR-HPV infections are cleared after conization, new evidence from numerous studies encourages the implementation of HR-HPV testing and genotyping to improve posttreatment surveillance. An HR-HPV test 6 months after conization is a promising useful clinical marker to detect persistence and prevent progression. This review highlights the clinical role of HPV testing in primary and secondary cervical cancer screening.
Description
Citation
Hoste, G., Vossaert, K., & Poppe, W. A. (2013). The Clinical Role of HPV Testing in Primary and Secondary Cervical Cancer Screening. Obstetrics and gynecology international, 2013, 610373. https://doi.org/10.1155/2013/610373
Publisher
Obstetrics and Gynecology International