Durable control and overall survival benefit with focal reirradiation in cervical cancer
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Authors
Amini, Arya
Sumner, Whitney
Fisher, Christine M.
Issue Date
2015-12-11
Type
Article
Language
en_US
Keywords
Cervical Cancer , Recurrence , Reirradiation , Local Control , Lymph Node Recurrence , Intensity-Modulated Radiotherapy , Non-Central
Alternative Title
Abstract
Local recurrence following definitive chemoradiation in cervical cancer ranges from 5-18%. Currently, there are limited options available for patients recurring in para-aortic or iliac lymph nodes. We present two cases of reirradiation for non-central recurrences with intensity-modulated radiotherapy (IMRT). Both patients achieved a complete response with manageable short-term toxicities and no late adverse effects with a follow-up of over one year and three years after reirradiation. While further follow-up is needed, IMRT is a feasible and safe option in cervical cancer patients with recurrent in-field failures involving the lymph nodes.
Description
Citation
Amini, A., Sumner, W., & Fisher, C. M. (2015). Durable Control and Overall Survival Benefit with Focal Reirradiation in Cervical Cancer. Cureus, 7(12), e399. https://doi.org/10.7759/cureus.399
Publisher
Cureus