Recent developments on the roles of calcium signals and potential therapy targets in cervical cancer
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Authors
Lei, Jiahui
Deng, Fengying
Ding, Hongmei
Fu, Mengyu
Xu, Ting
Ji, Bingyu
Feng, Lin
Li, Min
Qiu, Junlan
Gao, Qinqin
Issue Date
2022-09-26
Type
Article
Language
en_US
Keywords
Cervical Cancer , Ca2+ Signals , Occurrence , Development , Prognosis
Alternative Title
Abstract
Intracellular calcium (Ca2+) concentration ([Ca2+]i) is implicated in proliferation, invasion, and metastasis in cancerous tissues. A variety of oncologic therapies and some candidate drugs induce their antitumor effects (in part or in whole) through the modulation of [Ca2+]i. Cervical cancer is one of most common cancers among women worldwide. Recently, major research advances relating to the Ca2+ signals in cervical cancer are emerging. In this review, we comprehensively describe the current progress concerning the roles of Ca2+ signals in the occurrence, development, and prognosis of cervical cancer. It will enhance our understanding of the causative mechanism of Ca2+ signals in cervical cancer and thus provide new sights for identifying potential therapeutic targets for drug discovery.
Description
Citation
Lei, J., Deng, F., Ding, H., Fu, M., Xu, T., Ji, B., Feng, L., Li, M., Qiu, J., & Gao, Q. (2022). Recent Developments on the Roles of Calcium Signals and Potential Therapy Targets in Cervical Cancer. Cells, 11(19), 3003. https://doi.org/10.3390/cells11193003
Publisher
Cells