dbCerEx: a web-based database for the analysis of cervical cancer transcriptomes
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Authors
Zhou, Limin
Zheng, Wei
Luo, Majing
Feng, Jing
Jin, Zhichun
Wang, Yan
Zhang, Dunlan
Tang, Qiongxiu
He, Yan
Issue Date
2014-06-11
Type
Article
Language
en_US
Keywords
Web-Based Database , Analysis of Cervical Cancer Transcriptomes
Alternative Title
Abstract
Background:
Cervical cancers are ranked the second-most hazardous ailments among women worldwide. In the past two decades, microarray technologies have been applied to study genes involved in malignancy progress. However, in most of the published microarray studies, only a few genes were reported leaving rather a large amount of data unused. Also, RNA-Seq data has become more standard for transcriptome analysis and is widely applied in cancer studies. There is a growing demand for a tool to help the experimental researchers who are keen to explore cervical cancer gene therapy, but lack computer expertise to access and analyze the high throughput gene expression data.
Description:
The dbCerEx database is designed to retrieve and process gene expression data from cervical cancer samples. It includes the genome wide expression profiles of cervical cancer samples, as well as a web utility to cluster genes with similar expression patterns. This feature will help researchers conduct further research to uncover novel gene functions.
Conclusion:
The dbCerEx database is freely available for non-commercial use at http://128.135.207.10/dbCerEx/, and will be updated and integrated with more features as needed.
Description
Citation
Zhou, L., Zheng, W., Luo, M., Feng, J., Jin, Z., Wang, Y., Zhang, D., Tang, Q., & He, Y. (2014). dbCerEx: a web-based database for the analysis of cervical cancer transcriptomes. PloS one, 9(6), e99834. https://doi.org/10.1371/journal.pone.0099834
Publisher
PloS One