Microbiota and human reproduction: the case of female infertility
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Authors
Tomaiuolo, Rossella
Veneruso, Iolanda
Cariati, Federica
D’Argenio, Valeria
Issue Date
2020-05-03
Type
Article
Language
en_US
Keywords
Microbiota , Human Microbiome , Human Reproduction , Female Reproductive System , Female Infertility
Alternative Title
Abstract
During the last decade, the availability of next-generation sequencing-based approaches has revealed the presence of microbial communities in almost all the human body, including the reproductive tract. As for other body sites, this resident microbiota has been involved in the maintenance of a healthy status. As a consequence, alterations due to internal or external factors may lead to microbial dysbiosis and to the development of pathologies. Female reproductive microbiota has also been suggested to affect infertility, and it may play a key role in the success of assisted reproductive technologies, such as embryo implantation and pregnancy care. While the vaginal microbiota is well described, the uterine microbiota is underexplored. This could be due to technical issues, as the uterus is a low biomass environment. Here, we review the state of the art regarding the role of the female reproductive system microbiota in women’s health and human reproduction, highlighting its contribution to infertility.
Description
Citation
Tomaiuolo, R., Veneruso, I., Cariati, F., & D'Argenio, V. (2020). Microbiota and Human Reproduction: The Case of Female Infertility. High-throughput, 9(2), 12. https://doi.org/10.3390/ht9020012
Publisher
High-throughput