Clinical assessment of the male fertility
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Authors
Khatun, Amena
Rahman, Saidur
Pang, Myung-Geol
Issue Date
2018-03-05
Type
Article
Language
en_US
Keywords
Male Fertility , Semen Analysis , Spermatozoa
Alternative Title
Abstract
The evaluation of infertility in males consists of physical examination and semen analyses. Standardized semen analyses depend on the descriptive analysis of sperm motility, morphology, and concentration, with a threshold level that must be surpassed to be considered a fertile spermatozoon. Nonetheless, these conventional parameters are not satisfactory for clinicians since 25% of infertility cases worldwide remain unexplained. Therefore, newer tests methods have been established to investigate sperm physiology and functions by monitoring characteristics such as motility, capacitation, the acrosome reaction, reactive oxygen species, sperm DNA damage, chromatin structure, zona pellucida binding, and sperm-oocyte fusion. After the introduction of intracytoplasmic sperm injection technique, sperm maturity, morphology, and aneuploidy conditions have gotten more attention for investigating unexplained male infertility. In the present article, recent advancements in research regarding the utilization of male fertility prediction tests and their role and accuracy are reviewed.
Description
Citation
Khatun, A., Rahman, M. S., & Pang, M. G. (2018). Clinical assessment of the male fertility. Obstetrics & gynecology science, 61(2), 179–191. https://doi.org/10.5468/ogs.2018.61.2.179
Publisher
Obstetrics & Gynecology Science