Letrozole for female infertility

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Authors
Yang, Ai-Min
Cui, Na
Sun, Yi-Fei
Hao, Gui-Min
Issue Date
2021-06-16
Type
Article
Language
en_US
Keywords
Letrozole , Ovulation Induction (OI) , Frozen-Thawed Embryo Transfer , Fertility Preservation , Endometrium Preparation , Female Infertility
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Abstract
Letrozole, an aromatase inhibitor that blocks estrogen synthesis by inhibiting the final step of the estrogen biosynthetic pathway, has been used in the applications of a wide range of infertility settings. It has been more than 20 years since the initial clinical trial of letrozole for ovulation induction. In light of the accumulating clinical and basic evidence, the efficacy and safety of letrozole have been identified. This mini review focuses on our current knowledge of the applications and mechanisms of letrozole for female infertility and various questions are put forward about how letrozole could be more effectively used.
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Citation
Yang, A. M., Cui, N., Sun, Y. F., & Hao, G. M. (2021). Letrozole for Female Infertility. Frontiers in endocrinology, 12, 676133. https://doi.org/10.3389/fendo.2021.676133
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Frontiers in Endocrinology
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