Health concerns regarding the effect of the COVID-19 pandemic on male fertility
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Authors
Mosleh, Hamidreza
Moradi, Fatemeh
Mehdizadeh, Mehdi
Ajdary, Marziyeh
Moeinzadeh, Alaa
Shabani, Ronak
Issue Date
2021-07-22
Type
Article
Language
en_US
Keywords
COVID-19 , Male Fertility , Health Concerns
Alternative Title
Abstract
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a novel coronavirus found in China in 2019. The disease caused by SARS-CoV-2, coronavirus disease 2019 (COVID-19), has been found to be closely related to the cells that secrete angiotensin-converting enzyme 2 (ACE2). ACE2 is involved in the renin-angiotensin system and is widely secreted in several tissues, including the testis, which has raised concerns because organs with high expression of the ACE2 receptor are susceptible to infection. Analyses have shown that in testicular cells, such as spermatogonia, seminiferous duct cells, Sertoli cells, and Leydig cells, there is a high expression level of ACE2. Therefore, SARS-CoV-2 may damage male reproductive tissues and cause infertility. Since male infertility is an important problem, scientists are evaluating whether COVID-19 may influence male infertility through the ACE2 receptor.
Description
Citation
Mosleh, H., Moradi, F., Mehdizadeh, M., Ajdary, M., Moeinzadeh, A., & Shabani, R. (2021). Health concerns regarding the effect of the COVID-19 pandemic on male fertility. Clinical and experimental reproductive medicine, 48(3), 189–193. https://doi.org/10.5653/cerm.2021.04378
Publisher
Clinical and Experimental Reproductive Medicine