The menstrual disturbances in endocrine disorders: a narrative review
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Authors
Naz, Marzieh Saei Ghare
Dovom, Marzieh Rostami
Tehrani, Fahimeh Ramezani
Issue Date
2020-10-14
Type
Article
Language
en_US
Keywords
Menstruation , Endocrine System Diseases , Menstrual Cycle , Review
Alternative Title
Abstract
Context:
Menstrual cycle is considered the fifth vital sign among women. This study aimed to summarize the menstrual disturbances in different endocrine disorders.
Evidence Acquisition:
In this narrative review, relevant studies (up to December 2019) were searched based on the MeSH keywords diabetes, polycystic ovary syndrome, Cushing’s syndrome, thyroid dysfunction, hyperprolactinemia, menstrual cycle, uterine bleeding, and menstruation. Databases used for searching articles included Google Scholar, Scopus, PubMed, and Web of science for observational, experimental, and review studies.
Results:
Endocrine disorders trigger the onset of menstrual disturbance across the reproductive lifespan of women. Endocrine glands (pituitary, thyroid, pancreas, adrenal, and ovaries) have a functional role in endocrine regulation of the menstrual cycle. According to available evidence, oligomenorrhea (cycles longer than 35 days) is the most common menstrual disturbance among endocrine disorders (thyrotoxicosis, hypothyroidism, polycystic ovary syndrome, Cushing’s syndrome, and diabetes). Complex endocrine pathways play an essential role in a women’s menstrual calendar.
Conclusions:
The menstrual cycle length and amount of bleeding can be indicative of endocrine disorders. Further studies are needed to identify the unknowns about the association between endocrine disorders and the menstrual cycle.
Description
Citation
Saei Ghare Naz, M., Rostami Dovom, M., & Ramezani Tehrani, F. (2020). The Menstrual Disturbances in Endocrine Disorders: A Narrative Review. International journal of endocrinology and metabolism, 18(4), e106694. https://doi.org/10.5812/ijem.106694
Publisher
International Journal of Endocrinology and Metabolism