The menstrual cycle and risk of breast cancer: a review
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Authors
Olsson, Håkan Lars
Olsson, Mona Landin
Issue Date
2020-01
Type
Article
Language
en_US
Keywords
Breast Cancer , Menstrual Cycle , Risk , Retrospective
Alternative Title
Abstract
Cyclic hormonal stimulation of the breast tissue plays a significant role in breast carcinogenesis. Current risk factor models do not include direct measures of cycle characteristics although the effects of possible surrogates of cycle activity such as age at menarche and menopause, parity, and nursing time have been investigated. Future risk models should also include menstrual cycle length, regularity, number of cycles before first full-term pregnancy, and life-time number of cycles. New risk factor models for pre- and postmenopausal breast cancer are proposed here. Furthermore, there is a need for more long-term, prospective studies investigating menstrual cycle characteristics as data currently available are primarily retrospective and collected at one time-point only.
Description
Citation
Olsson, H. L., & Olsson, M. L. (2020). The Menstrual Cycle and Risk of Breast Cancer: A Review. Frontiers in oncology, 10, 21. https://doi.org/10.3389/fonc.2020.00021
Publisher
Frontiers in Oncology