Nutrition, genetic variation and male fertility
Loading...
Authors
Vanderhout, Shelley M.
Panah, Matineh Rastegar
Garcia-Bailo, Bibiana
Grace-Farfaglia, Patricia
Samsel, Konrad
Dockray, Judith
Jarvi, Keith
El-Sohemy, Ahmed
Issue Date
2021-03
Type
Article
Language
en_US
Keywords
Micronutrients , Reproduction , Male Fertility , Nutrition , Genetics , Nutrigenomics , Nutrigenetics
Alternative Title
Abstract
Infertility affects nearly 50 million couples worldwide, with 40−50% of cases having a male factor component. It is well established that nutritional status impacts reproductive development, health and function, although the exact mechanisms have not been fully elucidated. Genetic variation that affects nutrient metabolism may impact fertility through nutrigenetic mechanisms. This review summarizes current knowledge on the role of several dietary components (vitamins A, B12, C, D, E, folate, betaine, choline, calcium, iron, caffeine, fiber, sugar, dietary fat, and gluten) in male reproductive health. Evidence of gene-nutrient interactions and their potential effect on fertility is also examined. Understanding the relationship between genetic variation, nutrition and male fertility is key to developing personalized, DNA-based dietary recommendations to enhance the fertility of men who have difficulty conceiving.
Description
Citation
Vanderhout, S. M., Rastegar Panah, M., Garcia-Bailo, B., Grace-Farfaglia, P., Samsel, K., Dockray, J., Jarvi, K., & El-Sohemy, A. (2021). Nutrition, genetic variation and male fertility. Translational andrology and urology, 10(3), 1410–1431. https://doi.org/10.21037/tau-20-592
Publisher
Translational Andrology and Urology