Sexually transmitted infections in women participating in a biomedical intervention trial in Durban: prevalence, coinfections, and risk factors
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Authors
Abbai, Nathlee Samantha
Wand, Handan
Ramjee, Gita
Issue Date
2013-11-03
Type
Article
Language
en_US
Keywords
Sexually Transmitted Infections , Biomedical Intervention , Prevalence , Coinfections , Risk Factors
Alternative Title
Abstract
Background. Sexually transmitted infections (STIs) continue to be a significant public health problem especially among women of reproductive age in Africa. Methods. A total of 2236 women that had enrolled in the MDP301 vaginal microbicide trial were tested for the presence of Chlamydia trachomatis (CT), Neisseria gonorrhea (NG), Treponema pallidum, and Trichomonas vaginalis (TV). Results. CT was identified as the most prevalent STI (11%) followed by TV (10%), NG, and Syphilis (3%). The highest prevalence of coinfection was reported between T. pallidum and TV (19.67%, P = 0.004), followed by CT and TV (13.52%, P ≤ 0.001). Risk factors that were significantly associated with STI acquisition were women of 23 years of age or younger (HR: 1.50, 95% CI 1.17, 1.93), baseline STI with CT (HR: 1.77, 95% CI 1.32, 2.35), TV (HR: 1.58, 95% CI, 1.20, 2.10), and T. pallidum (HR: 5.13, 95% CI 3.65, 7.22), and a low education level (HR: 1.30, 95% CI 1.02, 1.66). Conclusion. Young women with lower education and a history of STIs are at high risk of multiple STIs. Prevention programs should consider target approach to STI prevention among young women. This trial is registered with ISRCTN64716212.
Description
Citation
Abbai, N. S., Wand, H., & Ramjee, G. (2013). Sexually Transmitted Infections in Women Participating in a Biomedical Intervention Trial in Durban: Prevalence, Coinfections, and Risk Factors. Journal of sexually transmitted diseases, 2013, 358402. https://doi.org/10.1155/2013/358402
Publisher
Journal of Sexually Transmitted Diseases