The other side of COVID‐19 pandemic: Effects on male fertility

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Authors
Seymen, Cemile Merve
Issue Date
2020-11-22
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Article
Language
en_US
Keywords
Genital Tract , Male Fertility , COVID-19
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Abstract
The outbreak of novel coronavirus disease 2019 (COVID‐19) has become a major pandemic threat worldwide. According to the existing clinical data, this virus not only causes respiratory diseases and affects the lungs but also induces histopathological or functional changes in various organs like the testis and also the male genital tract. The renin‐angiotensin system (RAS), also ACE 2 and TMPRSS2 play an important role in the cellular entry for SARS‐CoV‐2. Because the male genital system presents high ACE 2 expression, the importance of this pathway increases in COVID‐19 cases. As the COVID‐19 pandemic has affected the male genital system in direct or indirect ways and showed a negative impact on male reproduction, this paper focuses on the possible mechanisms underlying the damage caused by COVID‐19 to the testis and also other components of the male genital tract.
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This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.
Citation
Seymen C. M. (2021). The other side of COVID-19 pandemic: Effects on male fertility. Journal of medical virology, 93(3), 1396–1402. https://doi.org/10.1002/jmv.26667
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Journal of Medical Virology
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